| 2021 Week 12
- Bye:
- Atlanta Falcons 21, Jacksonville Jaguars 14 -- Box Score
- Baltimore Ravens 16, Cleveland Browns 10 -- Box Score
- Buffalo Bills 31, New Orleans Saints 6 -- Box Score
- Chicago Bears 16, Detroit Lions 14 -- Box Score
- Cincinnati Bengals 41, Pittsburgh Steelers 10 -- Box Score
- Denver Broncos 28, Los Angeles Chargers 13 -- Box Score
- Green Bay Packers 36, Los Angeles Rams 28 -- Box Score
- Las Vegas Raiders 36, Dallas Cowboys 33 (OT) -- Box Score
- Miami Dolphins 33, Carolina Panthers 10 -- Box Score
- New England Patriots 36, Tennessee Titans 13 -- Box Score
- New York Giants 13, Philadelphia Eagles 7 -- Box Score
- New York Jets 21, Houston Texans 14 -- Box Score
- San Francisco 49ers 34, Minnesota Vikings 26 -- Box Score
- Tampa Bay Buccaneers 38, Indianapolis Colts 31 -- Box Score
- Washington Football Team 17, Seattle Seahawks 15 -- Box Score
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