| 2000 Week 1
- Bye:
- Atlanta Falcons 36, San Francisco 49ers 28 -- Box Score
- Baltimore Ravens 16, Pittsburgh Steelers 0 -- Box Score
- Buffalo Bills 16, Tennessee Titans 13 -- Box Score
- Detroit Lions 14, New Orleans Saints 10 -- Box Score
- Indianapolis Colts 27, Kansas City Chiefs 14 -- Box Score
- Jacksonville Jaguars 27, Cleveland Browns 7 -- Box Score
- Miami Dolphins 23, Seattle Seahawks 0 -- Box Score
- Minnesota Vikings 30, Chicago Bears 27 -- Box Score
- New York Giants 21, Arizona Cardinals 16 -- Box Score
- New York Jets 20, Green Bay Packers 16 -- Box Score
- Oakland Raiders 9, San Diego Chargers 6 -- Box Score
- Philadelphia Eagles 41, Dallas Cowboys 14 -- Box Score
- St. Louis Rams 41, Denver Broncos 36 -- Box Score
- Tampa Bay Buccaneers 21, New England Patriots 16 -- Box Score
- Washington Redskins 20, Carolina Panthers 17 -- Box Score
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