| San Diego Chargers 28,
Indianapolis Colts 24
| First Quarter |
 | Ind--D.Clark 25 pass from P.Manning (A.Vinatieri kick), 5:47. |
| Second Quarter |
| SD--V.Jackson 14 pass from P.Rivers (N.Kaeding kick), 6:22.
Ind--FG A.Vinatieri 46, 9:50. |
| Third Quarter |
| SD--C.Chambers 30 pass from P.Rivers (N.Kaeding kick), 3:27.
Ind--R.Wayne 9 pass from P.Manning (A.Vinatieri kick), 12:07.
SD--D.Sproles 56 pass from P.Rivers (N.Kaeding kick), 15:00. |
| Fourth Quarter |
| Ind--A.Gonzalez 55 pass from P.Manning (A.Vinatieri kick), 4:53.
SD--B.Volek 1 run (N.Kaeding kick), 10:10. |
| A--56,950. |
| | SD | IND |
| FIRST DOWNS | 20 | 29 |
| Rushing | 4 | 4 |
| Passing | 14 | 21 |
| Penalty | 2 | 4 |
| 3RD-DOWN EFFICIENCY | 6-10 | 3-11 |
| 4TH-DOWN EFFICIENCY | 0-0 | 2-4 |
| TOTAL NET YARDS | 411 | 446 |
| Total Plays | 53 | 66 |
| Average Gain | 7.8 | 6.8 |
| NET YARDS RUSHING | 99 | 44 |
| Rushes | 30 | 18 |
| Average per Rush | 3.3 | 2.4 |
| NET YARDS PASSING | 312 | 402 |
| Completed - Attempted | 17-23 | 33-48 |
| Yards per Pass | 13.6 | 8.4 |
| Sacked - Yards Lost | 0-0 | 0-0 |
| Had Intercepted | 1 | 2 |
| PUNTS-AVERAGE | 3-59.0 | 1-49.0 |
| RETURN YARDAGE | 133 | 176 |
| Punt Returns - Yards | 0-0 | 3-46 |
| Kickoff Returns - Yards | 4-103 | 5-129 |
| Int. Returns - Yards | 2-30 | 1-1 |
| PENALTIES-YARDS | 10-79 | 5-54 |
| FUMBLES-LOST | 1-0 | 1-1 |
| TIME OF POSSESSION | 29:39 | 30:21 |
| INDIVIDUAL STATISTICS |
| RUSHING -- |
| | SD: | M.Turner 17-71, L.Tomlinson 7-28, D.Sproles 1-1, P.Rivers 2-0, B.Volek 3-(-1). |
| | IND: | J.Addai 13-43, K.Keith 4-7, P.Manning 1-(-6). |
| PASSING -- |
| | SD: | P.Rivers 14-19-264-3-1, B.Volek 3-4-48-0-0. |
| | IND: | P.Manning 33-48-402-3-2. |
| RECEIVING -- |
| | SD: | V.Jackson 7-93, C.Chambers 3-67, A.Gates 2-28, D.Sproles 1-56, L.Naanee 1-27, L.Tomlinson 1-20, C.Davis 1-18, B.Manumaleuna 1-3. |
| | IND: | J.Addai 9-67, R.Wayne 7-76, D.Clark 6-95, A.Gonzalez 4-79, M.Harrison 2-27, K.Keith 2-23, B.Utecht 1-20, D.Aromashodu 1-13, B.Fletcher 1-2. |
| MISSED FIELD GOALS -- |
| | SD: | N.Kaeding 48. |
|