| San Francisco 49ers 23,
Carolina Panthers 10
| First Quarter |
 | SF--FG P.Dawson 49, 5:48.
SF--FG P.Dawson 33, 10:27. |
| Second Quarter |
| Car--S.Smith 31 pass from C.Newton (G.Gano kick), 1:20.
Car--FG G.Gano 24, 11:19.
SF--V.Davis 1 pass from C.Kaepernick (P.Dawson kick) |
| Third Quarter |
| SF--C.Kaepernick 4 run (P.Dawson kick), 6:07. |
| Fourth Quarter |
| SF--FG P.Dawson 34, 7:25. |
| A--73,784. |
| | SF | CAR |
| FIRST DOWNS | 21 | 18 |
| Rushing | 5 | 7 |
| Passing | 11 | 9 |
| Penalty | 5 | 2 |
| 3RD-DOWN EFFICIENCY | 6-14 | 6-10 |
| 4TH-DOWN EFFICIENCY | 0-1 | 0-1 |
| TOTAL NET YARDS | 315 | 325 |
| Total Plays | 65 | 54 |
| Average Gain | 4.8 | 6.0 |
| NET YARDS RUSHING | 126 | 93 |
| Rushes | 34 | 24 |
| Average per Rush | 3.7 | 3.9 |
| NET YARDS PASSING | 189 | 232 |
| Completed - Attempted | 15-30 | 16-25 |
| Yards per Pass | 6.1 | 7.7 |
| Sacked - Yards Lost | 1-7 | 5-35 |
| Had Intercepted | 0 | 2 |
| PUNTS-AVERAGE | 2-47.5 | 2-42.0 |
| RETURN YARDAGE | 17 | 105 |
| Punt Returns - Yards | 0-0 | 2-27 |
| Kickoff Returns - Yards | 0-0 | 4-78 |
| Int. Returns - Yards | 2-17 | 0-0 |
| PENALTIES-YARDS | 5-40 | 8-73 |
| FUMBLES-LOST | 1-0 | 0-0 |
| TIME OF POSSESSION | 29:55 | 30:05 |
| INDIVIDUAL STATISTICS |
| RUSHING -- |
| | SF: | F.Gore 17-84, K.Hunter 9-27, C.Kaepernick 8-15. |
| | CAR: | C.Newton 10-54, M.Tolbert 8-20, D.Williams 5-13, B.LaFell 1-6. |
| PASSING -- |
| | SF: | C.Kaepernick 15-28-196-1-0, A.Boldin 0-1-0-0-0, A.Lee 0-1-0-0-0. |
| | CAR: | C.Newton 16-25-267-1-2 |
| RECEIVING -- |
| | SF: | A.Boldin 8-136, M.Crabtree 3-26, Q.Patton 1-23, F.Gore 1-8, W.Tukuafu 1-2, V.Davis 1-1. |
| | CAR: | T.Ginn 4-104, S.Smith 4-74, G.Olsen 4-55, B.LaFell 4-34. |
|