| Houston Texans 22,
Buffalo Bills 19 (OT)
| First Quarter |
 | Buf--J.Allen 16 pass from J.Brown (S.Hauschka kick), 3:19. |
| Second Quarter |
| Buf--FG S.Hauschka 40, 4:13.
Buf--FG S.Hauschka 40, 14:56. |
| Third Quarter |
| Buf--FG S.Hauschka 38, 8:58.
Hou--D.Watson 20 run (D.Watson run), 13:27. |
| Fourth Quarter |
| Hou--FG K.Fairbairn 41, 4:05.
Hou--C.Hyde 5 pass from D.Watson (D.Hopkins pass from D.Watson), 10:23.
Buf--FG S.Hauschka 47, 14:55. |
| Overtime |
| Hou--FG K.Fairbairn 28, 11:40. |
| A--71,699. |
| | BUF | HOU |
| FIRST DOWNS | 24 | 19 |
| Rushing | 10 | 5 |
| Passing | 14 | 13 |
| Penalty | 0 | 1 |
| 3RD-DOWN EFFICIENCY | 11-21 | 6-13 |
| 4TH-DOWN EFFICIENCY | 0-1 | 0-1 |
| TOTAL NET YARDS | 425 | 360 |
| Total Plays | 81 | 65 |
| Average Gain | 5.2 | 5.5 |
| NET YARDS RUSHING | 172 | 141 |
| Rushes | 30 | 33 |
| Average per Rush | 5.7 | 4.3 |
| NET YARDS PASSING | 253 | 219 |
| Completed - Attempted | 25-48 | 20-25 |
| Yards per Pass | 5.0 | 6.8 |
| Sacked - Yards Lost | 3-27 | 7-28 |
| Had Intercepted | 0 | 0 |
| PUNTS-AVERAGE | 4-44.8 | 5-43.2 |
| RETURN YARDAGE | 8 | 26 |
| Punt Returns - Yards | 1-8 | 1-11 |
| Kickoff Returns - Yards | 0-0 | 2-15 |
| Int. Returns - Yards | 0-0 | 0-0 |
| PENALTIES-YARDS | 7-64 | 4-20 |
| FUMBLES-LOST | 2-1 | 2-1 |
| TIME OF POSSESSION | 35:15 | 36:25 |
| INDIVIDUAL STATISTICS |
| RUSHING -- |
| | BUF: | J.Allen 9-92, D.Singletary 13-58, F.Gore 8-22. |
| | HOU: | D.Watson 14-55, C.Hyde 16-48, D.Johnson 3-38. |
| PASSING -- |
| | BUF: | J.Brown 1-1-16-1-0, J.Allen 24-46-264-0-0, C.Bojorquez 0-1-0-0-0. |
| | HOU: | D.Watson 20-25-247-1-0. |
| RECEIVING -- |
| | BUF: | D.Singletary 6-76, J.Brown 4-50, D.Williams 4-49, C.Beasley 4-44, I.McKenzie 4-23, J.Allen 1-16, D.Knox 1-14, L.Smith 1-8. |
| | HOU: | D.Hopkins 6-90, K.Stills 4-46, D.Fells 4-37, D.Johnson 3-30, T.Jones 1-34, D.Carter 1-5, C.Hyde 1-5. |
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