| 1981 Week 16
- Baltimore Colts 23, New England Patriots 21
- Chicago Bears 35, Denver Broncos 24
- Cincinnati Bengals 30, Atlanta Falcons 28
- Houston Oilers 21, Pittsburgh Steelers 20
- Kansas City Chiefs 10, Minnesota Vikings 6
- Miami Dolphins 16, Buffalo Bills 6
- New York Giants 13, Dallas Cowboys 10 (OT)
- New York Jets 28, Green Bay Packers 3
- Philadelphia Eagles 38, St. Louis Cardinals 0
- San Diego Chargers 23, Oakland Raiders 10
- San Francisco 49ers 21, New Orleans Saints 17
- Seattle Seahawks 42, Cleveland Browns 21
- Tampa Bay Buccaneers 20, Detroit Lions 17
- Washington Redskins 30, Los Angeles Rams 7
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