| Week 5 Games
  Indianapolis Colts 12, Denver Broncos 9 (OT) |
| New York Giants 27, Green Bay Packers 22 at London, England |
| Buffalo Bills 38, Pittsburgh Steelers 3 |
| Houston Texans 13, Jacksonville Jaguars 6 |
| Los Angeles Chargers 30, Cleveland Browns 28 |
| Minnesota Vikings 29, Chicago Bears 22 |
| New England Patriots 29, Detroit Lions 0 |
| New Orleans Saints 39, Seattle Seahawks 32 |
| New York Jets 40, Miami Dolphins 17 |
| Tampa Bay Buccaneers 21, Atlanta Falcons 15 |
| Tennessee Titans 21, Washington Commanders 17 |
| San Francisco 49ers 37, Carolina Panthers 15 |
| Dallas Cowboys 22, Los Angeles Rams 10 |
| Philadelphia Eagles 20, Arizona Cardinals 17 |
| Baltimore Ravens 19, Cincinnati Bengals 17 |
| Kansas City Chiefs 30, Las Vegas Raiders 29 |
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