| 1965 AFL Rushing
| Rushing | Rush | Yds | Avg | TD | | Paul Lowe, SD | 222 | 1121 | 5.0 | 6 | | Cookie Gilchrist, DEN | 252 | 954 | 3.8 | 6 | | Clem Daniels, OAK | 219 | 884 | 4.0 | 5 | | Matt Snell, NYJ | 169 | 763 | 4.5 | 4 | | Curtis McClinton, KC | 175 | 661 | 3.8 | 6 | | Mack Lee Hill, KC | 125 | 627 | 5.0 | 2 | | Bill Mathis, NYJ | 147 | 604 | 4.1 | 5 | | Wray Carlton, BUF | 156 | 592 | 3.8 | 6 | | Ode Burrell, HOU | 130 | 528 | 4.1 | 3 | | Wendell Hayes, DEN | 130 | 526 | 4.0 | 5 | | Gene Foster, SD | 121 | 469 | 3.9 | 2 | | Billy Joe, BUF | 123 | 377 | 3.1 | 4 | | Jim Nance, BOS | 111 | 321 | 2.9 | 5 | | Keith Lincoln, SD | 74 | 302 | 4.1 | 3 | | Alan Miller, OAK | 73 | 272 | 3.7 | 1 | | Larry Garron, BOS | 74 | 259 | 3.5 | 1 | | Charley Tolar, HOU | 73 | 230 | 3.2 | 0 | | Babe Parilli, BOS | 50 | 200 | 4.0 | 0 | | Larry Todd, OAK | 32 | 183 | 5.7 | 0 | | Jack Spikes, HOU | 47 | 173 | 3.7 | 3 | | Roger Hagberg, OAK | 48 | 171 | 3.6 | 1 | | Abner Haynes, DEN | 41 | 166 | 4.0 | 3 | | J.D. Garrett, BOS | 42 | 147 | 3.5 | 1 | | Don Trull, HOU | 29 | 145 | 5.0 | 2 | | Len Dawson, KC | 43 | 142 | 3.3 | 2 | | Pete Beathard, KC | 25 | 138 | 5.5 | 4 | | Bert Coan, KC | 45 | 137 | 3.0 | 1 | | Bobby Smith, BUF | 43 | 137 | 3.2 | 1 | | Ron Burton, BOS | 45 | 108 | 2.4 | 1 | | Jim Allison, SD | 29 | 100 | 3.4 | 0 | | Bob Scarpitto, DEN | 4 | 94 | 23.5 | 0 | | John Hadl, SD | 28 | 91 | 3.3 | 1 | | Bobby Jackson, HOU | 37 | 85 | 2.3 | 2 | | Mickey Slaughter, DEN | 20 | 75 | 3.8 | 0 | | Donnie Stone, BUF | 19 | 61 | 3.2 | 0 | | Mark Smolinski, NYJ | 24 | 59 | 2.5 | 0 | | Jack Kemp, BUF | 36 | 49 | 1.4 | 4 | | Joe Bellino, BOS | 24 | 49 | 2.0 | 0 | | Tom Flores, OAK | 11 | 32 | 2.9 | 0 | | Daryle Lamonica, BUF | 10 | 30 | 3.0 | 1 | | Ellis Johnson, BOS | 19 | 29 | 1.5 | 0 | | Frank Jackson, KC | 1 | 26 | 26.0 | 0 | | Kern Carson, SD/NYJ | 7 | 25 | 3.6 | 2 | | Paul Maguire, BUF | 1 | 21 | 21.0 | 0 | | Joe Namath, NYJ | 8 | 19 | 2.4 | 0 | | Joe Auer, BUF | 3 | 19 | 6.3 | 0 | | Odell Barry, DEN | 2 | 19 | 9.5 | 0 | | Jacque MacKinnon, SD | 3 | 17 | 5.7 | 0 | | Otis Taylor, KC | 2 | 17 | 8.5 | 0 | | Dick Wood, OAK | 4 | 16 | 4.0 | 1 | | Wahoo McDaniel, NYJ | 1 | 13 | 13.0 | 0 | | Dalton Hoffman, HOU | 1 | 11 | 11.0 | 0 | | Charley Frazier, HOU | 1 | 10 | 10.0 | 0 | | Walt Sweeney, SD | 0 | 8 | 0.0 | 0 | | Eddie Wilson, BOS | 8 | 4 | 0.5 | 0 | | Mike Taliaferro, NYJ | 7 | 4 | 0.6 | 0 | | Jerrel Wilson, KC | 2 | 4 | 2.0 | 0 | | Curley Johnson, NYJ | 2 | 3 | 1.5 | 0 | | Dick Compton, HOU | 1 | 2 | 2.0 | 0 | | Don Maynard, NYJ | 1 | 2 | 2.0 | 0 | | Charley Warner, BUF | 1 | 2 | 2.0 | 0 | | Jacky Lee, DEN | 2 | 1 | 0.5 | 0 | | Mike Mercer, OAK | 1 | -1 | -1.0 | 0 | | Don Breaux, SD | 1 | -1 | -1.0 | 0 | | John McCormick, DEN | 1 | -2 | -2.0 | 0 | | Al Denson, DEN | 1 | -4 | -4.0 | 0 | | Bo Roberson, OAK/BUF | 1 | -4 | -4.0 | 0 | | Don Norton, SD | 1 | -5 | -5.0 | 0 | | Pat Shea, SD | 1 | -5 | -5.0 | 0 | | George Blanda, HOU | 4 | -6 | -1.5 | 0 | | Lance Alworth, SD | 3 | -12 | -4.0 | 0 |
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