| 1981 Week 6
- Buffalo Bills 31, Miami Dolphins 21
- Cincinnati Bengals 41, Baltimore Colts 19
- Denver Broncos 27, Detroit Lions 21
- Houston Oilers 35, Seattle Seahawks 17
- Kansas City Chiefs 27, Oakland Raiders 0
- Los Angeles Rams 37, Atlanta Falcons 35
- Minnesota Vikings 33, San Diego Chargers 31
- New York Giants 34, St. Louis Cardinals 14
- New York Jets 28, New England Patriots 24
- Philadelphia Eagles 31, New Orleans Saints 14
- Pittsburgh Steelers 13, Cleveland Browns 7
- San Francisco 49ers 45, Dallas Cowboys 14
- Tampa Bay Buccaneers 21, Green Bay Packers 10
- Washington Redskins 24, Chicago Bears 7
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