| San Diego Chargers 23,
Indianapolis Colts 17 (OT)
| First Quarter |
 | Ind--J.Addai 1 run (A.Vinatieri kick), 12:01. |
| Second Quarter |
| SD--L.Tomlinson 3 run (N.Kaeding kick), 4:45.
Ind--FG A.Vinatieri 43, 8:14.
SD--D.Sproles 9 run (N.Kaeding kick), 14:18. |
| Third Quarter |
| Ind--R.Wayne 72 pass from P.Manning (A.Vinatieri kick), 6:50 |
| Fourth Quarter |
| SD--FG N.Kaeding 26, 14:29. |
| Overtime |
| SD--D.Sproles 22 run, 6:20. |
| A--68,082. |
| | IND | SD |
| FIRST DOWNS | 17 | 26 |
| Rushing | 5 | 11 |
| Passing | 11 | 12 |
| Penalty | 1 | 3 |
| 3RD-DOWN EFFICIENCY | 6-15 | 6-14 |
| 4TH-DOWN EFFICIENCY | 0-1 | 1-1 |
| TOTAL NET YARDS | 366 | 357 |
| Total Plays | 65 | 74 |
| Average Gain | 5.6 | 4.8 |
| NET YARDS RUSHING | 64 | 167 |
| Rushes | 22 | 34 |
| Average per Rush | 2.9 | 4.9 |
| NET YARDS PASSING | 302 | 190 |
| Completed - Attempted | 25-42 | 20-36 |
| Yards per Pass | 7.0 | 4.8 |
| Sacked - Yards Lost | 1-8 | 4-27 |
| Had Intercepted | 0 | 1 |
| PUNTS-AVERAGE | 6-46.8 | 6-52.7 |
| RETURN YARDAGE | 105 | 178 |
| Punt Returns - Yards | 2-6 | 3-72 |
| Kickoff Returns - Yards | 4-63 | 4-106 |
| Int. Returns - Yards | 1-36 | 0-0 |
| PENALTIES-YARDS | 9-74 | 3-40 |
| FUMBLES-LOST | 0-0 | 1-1 |
| TIME OF POSSESSION | 29:11 | 37:09 |
| INDIVIDUAL STATISTICS |
| RUSHING -- |
| | IND: | J.Addai 16-44, D.Rhodes 4-12, D.Clark 1-9, P.Manning 1-(-1). |
| | SD: | D.Sproles 23-105, L.Tomlinson 5-25, M.Bennett 4-24, P.Rivers 2-13. |
| PASSING -- |
| | IND: | P.Manning 25-42-310-1-0. |
| | SD: | P.Rivers 20-36-217-0-1. |
| RECEIVING -- |
| | IND: | D.Clark 7-33, A.Gonzalez 6-97, R.Wayne 4-129, J.Addai 4-28, M.Harrison 3-20, G.Robinson 1-3. |
| | SD: | A.Gates 8-87, D.Sproles 5-45, C.Chambers 4-57, L.Naanee 1-15, M.Bennett 1-7, J.Hester 1-6. |
|